Right, Transplantation of VEGF-expressing myoblasts into the myocardial walls
of mice results in the formation of a hemangioma
對，表達VEGF的成肌細胞移植到小鼠心肌壁導致血管瘤的形成
TRAIL could induce endothelial apoptosis and cause regression of hemangiomas.
TRAIL可誘導內皮細胞凋亡並導致血管瘤消退。
IFN-gamma enhances TRAIL-induced apoptosis through IRF-1.
IFN-γ通過IRF-1增強TRAIL誘導的細胞凋亡。
Enhancement of TRAIL-mediated apoptosis by IL-4 was blocked by anti-DR4-neutralizing antibodies.
IL-4增強TRAIL介導的細胞凋亡。
能提高IL-4的元素：鋅、維生素A、兒茶素、茄紅素、薑黃素、黃酮類化合物(蜂膠黃酮、生物類黃酮、大豆異黃酮)、鞣花酸
能提高IFN-γ的元素：鋅、硒、錳、維生素C、高劑量維生素E、茄紅素、大豆異黃酮、蜂膠黃酮、多醣體
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL)
is a new member of the TNF superfamily. In this work, the key role of Zn(2+)
in high-level expression of soluble TRAIL was confirmed.
腫瘤壞死因子（TNF）相關的凋亡誘導配體（Apo2L / TRAIL）是TNF超家族的新成員。
在這項工作中，證實了Zn（2+）(鋅)在可溶性TRAIL的高水平表達中的關鍵作用。
Zinc regulates vascular endothelial cell activity
鋅調節血管內皮細胞活性
Selenium induces apoptosis by upregulating TRAIL-R2/DR5, activating caspase-8
and cleaving Bid in human cancer cells (281–283)
硒通過上調TRAIL-R2 / DR5誘導細胞凋亡
維生素C上調TRAIL轉錄物（增加2.3倍）和增加TRAIL蛋白水平。
Alpha-tocopheryl succinate (alpha-TOS), a redox-inactive analogue of vitamin E
, is a strong inducer of apoptosis
α-生育酚琥珀酸酯（α-TOS）是維生素E的氧化還原非活性類似物，是細胞凋亡的強誘導物
Finally, alpha-TOS cooperated with tumor necrosis factor-related apoptosis-inducing ligand in suppression of tumor growth in vivo.
最後，α-TOS與腫瘤壞死因子相關的凋亡誘導配體(TRAIL)協同抑制體內腫瘤生長。
Vitamin E succinate (VES)
維生素E琥珀酸酯（VES）
On the other hand, the expression of TRAIL protein in human CD4+ T cells was obviously upregulated in the presence of VES.
另一方面，在VES存在下，TRAIL蛋白在人CD4 + T細胞中的表達明顯上調。
總結以上：
TRAIL導致血管瘤消退，鋅硒維它命C、E上調TRAIL，建議補充鋅硒維它命C、E治療血管瘤。